IN VITRO EVALUATION OF ANTHELMINTIC ACTIVITY OF AQUEOUS EXTRACT OF ARDISIA COLORATA ROXB. LEAVES IN ADULT EARTHWORMS

Objective: The study aims to evaluate the anthelmintic activity of aqueous extract Ardisia colorata Roxb. leaves (AQEAC) using adult earthworms (Pheretima posthuman).
 Methods: total 24 were divided into four groups, with six worms in each group (n=6). AQEAC at two different doses (25 mg/ml and 50 mg/ml) was evaluated by assessing time paralysis (min) death earthworms. Albendazole used as standard 2% gum acacia control.
 Results: result showed that AQEAChad significant (p<0.001) a dose-dependent manner but less potent than drug albendazole.
 Conclusion: demonstrated albendazole. However, further studies higher are required exact mechanism responsible for activity.